HMM Summary Page: TIGR03334

Functionindolepyruvate ferredoxin oxidoreductase, beta subunit
Gene SymboliorB
Trusted Cutoff205.80
Domain Trusted Cutoff205.80
Noise Cutoff88.70
Domain Noise Cutoff88.70
Isology Typeequivalog
EC Number1.2.7.8
HMM Length189
Gene Ontology TermGO:0016625: oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor molecular_function
AuthorHaft DH
Entry DateMar 6 2007 10:48PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents the beta subunit of indolepyruvate ferredoxin oxidoreductase, an alpha(2)/beta(2) tetramer, as found in Pyrococcus furiosus and Methanobacterium thermoautotrophicum. Cofactors for the tetramer include TPP, 4Fe4S, and 3Fe-4S. It shows considerable sequence similarity to subunits of several other ketoacid oxidoreductases.
ReferencesDR BRENDA; RN [1] RM PMID: 15262931 RT Two biosynthetic pathways for aromatic amino acids in the archaeon Methanococcus maripaludis. RA Porat I, Waters BW, Teng Q, Whitman WB RL J Bacteriol. 2004 Aug;186(15):4940-50. RN [2] RM PMID: 8206994 RT Indolepyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus. A new enzyme involved in peptide fermentation. RA Mai X, Adams MW RL J Biol Chem. 1994 Jun 17;269(24):16726-32.