HMM Summary Page: TIGR03316

Functionknotted carbamoyltransferase YgeW
Gene SymbolygeW
Trusted Cutoff500.00
Domain Trusted Cutoff500.00
Noise Cutoff300.00
Domain Noise Cutoff300.00
Isology Typeequivalog
EC Number2.1.3.-
HMM Length391
AuthorHaft DH
Entry DateFeb 21 2007 2:52PM
Last ModifiedNov 16 2011 8:02AM
CommentMembers of this protein family include the ygeW gene product of Escherichia coli. The function is unknown. Members show homology to ornithine carbamoyltransferase (TIGR00658) and aspartate carbamoyltransferase (carbamoyltransferase), and therefore may belong to the carbamoyltransferases in function. Members often are found in a large, conserved genomic region associated with selenium-dependent molybdenum hydroxylases.
ReferencesRN [1] RM PMID:21557323 RT The ygeW encoded protein from Escherichia coli is a knotted ancestral catabolic transcarbamylase. RA Li Y, Jin Z, Yu X, Allewell NM, Tuchman M, Shi D RL Proteins. 2011 Jul;79(7):2327-34. doi: 10.1002/prot.23043.