HMM Summary Page: TIGR03315

Functionputative selenate reductase, YgfK subunit
Gene SymbolygfK
Trusted Cutoff835.30
Domain Trusted Cutoff835.30
Noise Cutoff354.45
Domain Noise Cutoff354.45
Isology Typeequivalog
HMM Length1012
AuthorHaft DH
Entry DateFeb 15 2007 5:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are YgfK, predicted to be one subunit of a three-subunit, molybdopterin-containing selenate reductase. This enzyme is found, typically, in genomic regions associated with xanthine dehydrogenase homologs predicted to belong to the selenium-dependent molybdenum hydroxylases (SDMH). Therefore, the selenate reductase is suggested to play a role in furnishing selenide for SelD, the selenophosphate synthase.
ReferencesRN [1] RM PMID: 12480890 RT Involvement of a putative molybdenum enzyme in the reduction of selenate by Escherichia coli. RA Bebien M, Kirsch J, Mejean V, Vermeglio A RL Microbiology. 2002 Dec;148(Pt 12):3865-72. RN [2] RT Orphan SelD proteins and selenium-dependent molybdenum hydroxylases. RA Haft DH, Self WT RL Biology Direct 2008, 3:4
Genome PropertyGenProp0726: selenium-dependent molybdenum hydroxylase system (HMM)