Accession | TIGR03310 |
Name | matur_MocA_YgfJ |
Function | molybdenum cofactor cytidylyltransferase |
Gene Symbol | mocA |
Trusted Cutoff | 186.45 |
Domain Trusted Cutoff | 186.45 |
Noise Cutoff | 182.80 |
Domain Noise Cutoff | 182.80 |
Isology Type | equivalog |
EC Number | 2.7.7.76 |
HMM Length | 188 |
Author | Haft DH |
Entry Date | Feb 13 2007 3:49PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein include MocA, which transfers cytosine from CTP to molybdopterin during molybdopterin cytosine dinucleotide (MCD) cofactor biosynthesis. It is distantly related to MobA, the GTP:molybdopterin guanylyltransferase. The MocA family is particularly closely related in phylogenetic distribution to other markers of selenium-dependent molybdenum hydroxylases (SDMH), suggesting most SDMH must use MCD rather than molybdopterin guanine dinucleotide. |
References | RN [1]
RM PMID:18289380
RT Orphan SelD proteins and selenium-dependent molybdenum hydroxylases.
RA Haft DH, Self WT
RL Biol Direct. 2008 Feb 20;3:4.
RN [2]
RM PMID:19542235
RT MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli.
RA Neumann M, Mittelstadt G, Seduk F, Iobbi-Nivol C, Leimkuhler S
RL J Biol Chem. 2009 Aug 14;284(33):21891-8. |
Genome Property | GenProp0726: selenium-dependent molybdenum hydroxylase system (HMM) |