HMM Summary Page: TIGR03307

Functionphosphonate metabolism protein PhnP
Gene SymbolphnP
Trusted Cutoff272.25
Domain Trusted Cutoff272.25
Noise Cutoff188.20
Domain Noise Cutoff188.20
Isology Typeequivalog
HMM Length249
AuthorSelengut J
Entry DateFeb 9 2007 8:39AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family of proteins found in operons encoding phosphonate C-P lyase systems as is observed in E. coli [1] and is a member of the metallo-beta-lactamase superfamily (PF00753). As defined by this model, all instances of this protein are associated with the C-P lyase, but not all genomes containing the C-P lyase system contain phnP.
ReferencesRN [1] RM PMID: 2155230 RT Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B. RA Chen CM, Ye QZ, Zhu ZM, Wanner BL, Walsh CT RL J Biol Chem. 1990 Mar 15;265(8):4461-71.
Genome PropertyGenProp0232: phosphonates C-P lyase system (HMM)