HMM Summary Page: TIGR03302

Functionouter membrane assembly lipoprotein YfiO
Gene SymbolyfiO
Trusted Cutoff81.40
Domain Trusted Cutoff81.40
Noise Cutoff69.00
Domain Noise Cutoff69.00
Isology Typesubfamily
HMM Length239
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0005198: structural molecule activity molecular_function
GO:0006461: protein complex assembly biological_process
GO:0019867: outer membrane cellular_component
AuthorHaft DH
Entry DateFeb 1 2007 5:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795).
ReferencesRN [1] RM PMID: 16824102 RT YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. RA Malinverni JC, Werner J, Kim S, Sklar JG, Kahne D, Misra R, Silhavy TJ RL Mol Microbiol. 2006 Jul;61(1):151-64. RN [2] RM PMID: 8830266 RT A novel peptidoglycan-linked lipoprotein (ComL) that functions in natural transformation competence of Neisseria gonorrhoeae. RA Fussenegger M, Facius D, Meier J, Meyer TF RL Mol Microbiol. 1996 Mar;19(5):1095-105.
Genome PropertyGenProp0725: outer membrane protein assembly complex (HMM)