HMM Summary Page: TIGR03294

Functioncoenzyme F420 hydrogenase, subunit gamma
Gene SymbolfrhG
Trusted Cutoff245.50
Domain Trusted Cutoff245.50
Noise Cutoff167.65
Domain Noise Cutoff167.65
Isology Typeequivalog
EC Number1.12.98.1
HMM Length228
AuthorSelengut J
Entry DateJan 25 2007 2:42PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents that clade of F420-dependent hydrogenases (FRH) beta subunits [1] found exclusively and universally in methanogenic archaea. This protein contains two 4Fe-4S cluster binding domains (PF00037) and scores above the trusted cutoff to model PF01058 for the "NADH ubiquinone oxidoreductase, 20 Kd subunit" family.
ReferencesRN [1] RM PMID: 2207102 RT Cloning, sequence determination, and expression of the genes encoding the subunits of the nickel-containing 8-hydroxy-5-deazaflavin reducing hydrogenase from Methanobacterium thermoautotrophicum delta H. RA Alex LA, Reeve JN, Orme-Johnson WH, Walsh CT RL Biochemistry. 1990 Aug 7;29(31):7237-44.
Genome PropertyGenProp0723: hydrogenase, nickel and F420-dependent (HMM)