HMM Summary Page: TIGR03278

Functionmethanogenesis marker radical SAM protein
Trusted Cutoff350.00
Domain Trusted Cutoff350.00
Noise Cutoff250.00
Domain Noise Cutoff250.00
Isology Typeequivalog
HMM Length404
AuthorHaft DH
Entry DateJan 19 2007 2:13PM
Last ModifiedFeb 10 2012 11:29AM
CommentMembers of this protein family, to date, are found in a completed prokaryotic genome if and only if the species is one of the archaeal methanogens. It is a radical SAM enzyme by homology. The exact function is unknown, but likely is linked to methanogenesis. In most genomes, the member of this family is encoded by a gene next to, and divergently transcribed from, the methyl coenzyme M reductase operon.
ReferencesRN [1] RM PMID:22070167 RT ProPhylo: partial phylogenetic profiling to guide protein family construction and assignment of biological process. RA Basu MK, Selengut JD, Haft DH RL BMC Bioinformatics. 2011 Nov 9;12:434.
Genome PropertyGenProp0722: methanogenesis marker set (HMM)