HMM Summary Page: TIGR03269

Functionmethyl coenzyme M reductase system, component A2
Gene SymbolatwA
Trusted Cutoff517.10
Domain Trusted Cutoff517.10
Noise Cutoff410.90
Domain Noise Cutoff410.90
Isology Typeequivalog
HMM Length530
Mainrole CategoryEnergy metabolism
Subrole CategoryMethanogenesis
AuthorHaft DH
Entry DateJan 17 2007 11:11AM
Last ModifiedFeb 14 2011 3:27PM
CommentThe enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2.
ReferencesRN [1] RM PMID: 8491734 RT Component A2 of methylcoenzyme M reductase system from Methanobacterium thermoautotrophicum delta H: nucleotide sequence and functional expression by Escherichia coli. RA Kuhner CH, Lindenbach BD, Wolfe RS RL J Bacteriol. 1993 May;175(10):3195-203.
Genome PropertyGenProp0719: methyl-coenzyme M reductase (HMM)
GenProp0722: methanogenesis marker set (HMM)