| Accession | TIGR03264 |
| Name | met_CoM_red_C |
| Function | methyl-coenzyme M reductase I operon protein C |
| Gene Symbol | mcrC |
| Trusted Cutoff | 213.50 |
| Domain Trusted Cutoff | 213.50 |
| Noise Cutoff | 51.55 |
| Domain Noise Cutoff | 51.55 |
| Isology Type | equivalog |
| HMM Length | 194 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Methanogenesis |
| Author | Haft DH |
| Entry Date | Jan 16 2007 3:54PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are protein C, a non-structural protein, of the operon for methyl coenzyme M reductase, also called coenzyme-B sulfoethylthiotransferase (EC 2.8.4.1). That enzyme, with alpha, beta, and gamma subunits, catalyzes the last step in methanogenesis; it
has several modified sites, so accessory proteins are expected. Several methanogens have encode two such enzymes, designated I and II; this protein occurs only operons of type I. The precise function is unknown. |
| References | RN [1]
RM PMID: 8359675
RT Identification of the mcrC gene product in Methanococcus vannielii.
RA Stroup D, Reeve JN
RL FEMS Microbiol Lett. 1993 Jul 15;111(1):129-34.
RN [2]
RM PMID: 8177216
RT Characterization and phylogeny of mcrII, a gene cluster encoding an isoenzyme of methyl coenzyme M reductase from hyperthermophilic Methanothermus fervidus.
RA Lehmacher A, Klenk HP
RL Mol Gen Genet. 1994 Apr;243(2):198-206. |
| Genome Property | GenProp0719: methyl-coenzyme M reductase (HMM) |
| | GenProp0722: methanogenesis marker set (HMM) |
