HMM Summary Page: TIGR03256

Functionmethyl-coenzyme M reductase, alpha subunit
Gene SymbolmcrA
Trusted Cutoff767.75
Domain Trusted Cutoff767.75
Noise Cutoff314.45
Domain Noise Cutoff314.45
Isology Typeequivalog
EC Number2.8.4.1
HMM Length548
Mainrole CategoryEnergy metabolism
Subrole CategoryMethanogenesis
AuthorHaft DH
Entry DateJan 12 2007 4:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the alpha subunit of methyl coenzyme M reductase, also called coenzyme-B sulfoethylthiotransferase (EC This enzyme, with alpha, beta, and gamma subunits, catalyzes the last step in methanogenesis. Several methanogens have encode two such enzymes, designated I and II; this model does not separate the isozymes.
Genome PropertyGenProp0719: methyl-coenzyme M reductase (HMM)
GenProp0722: methanogenesis marker set (HMM)