HMM Summary Page: TIGR03248

Functiongalactarate dehydratase
Gene SymbolgarD
Trusted Cutoff730.85
Domain Trusted Cutoff730.85
Noise Cutoff634.95
Domain Noise Cutoff634.95
Isology Typeequivalog
EC Number4.2.1.42
HMM Length507
AuthorSelengut J
Entry DateJan 9 2007 10:55AM
Last ModifiedFeb 14 2011 3:27PM
CommentGalactarate dehydratase converts D-galactarate to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase ([1], GenProp0714).
ReferencesRN [1] RM PMID: 9772162 RT Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. RA Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA RL Biochemistry. 1998 Oct 13;37(41):14369-75.