HMM Summary Page: TIGR03246

Functionsuccinylornithine transaminase family
Gene SymbolastC
Trusted Cutoff609.95
Domain Trusted Cutoff609.95
Noise Cutoff579.10
Domain Noise Cutoff579.10
Isology Typesubfamily
EC Number2.6.1.81
HMM Length397
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
AuthorHaft DH
Entry DateJan 8 2007 1:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of the seed alignment for this protein family are the enzyme succinylornithine transaminase (EC, which catalyzes the third of five steps in arginine succinyltransferase (AST) pathway, an ammonia-releasing pathway of arginine degradation. All seed alignment sequences are found within arginine succinyltransferase operons, and all proteins that score above 820.0 bits should function as succinylornithine transaminase. However, a number of sequences extremely closely related in sequence, found in different genomic contexts, are likely to act in different biological processes and may act on different substrates. This model is desigated subfamily rather than equivalog, pending further consideration, for this reason.
Genome PropertyGenProp0309: arginine catabolism to glutamate via arginine succinyltransferase (AST) (HMM-CLUST)