HMM Summary Page: TIGR03244

Functionarginine N-succinyltransferase
Gene SymbolastA
Trusted Cutoff391.00
Domain Trusted Cutoff391.00
Noise Cutoff358.20
Domain Noise Cutoff358.20
Isology Typeequivalog
EC Number2.3.1.109
HMM Length336
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0006527: arginine catabolic process biological_process
GO:0008791: arginine N-succinyltransferase activity molecular_function
AuthorHaft DH
Entry DateJan 6 2007 9:48AM
Last ModifiedFeb 14 2011 3:27PM
CommentIn many bacteria, the arginine succinyltransferase (ast) pathway operon consists of five genes, including this protein, arginine N-succinyltransferase (EC In a few species, such as Pseudomonas aeruginosa, the member of this family is encoded adjacent to a paralog, and the two polypeptides form a heterodimeric enzyme, active on both arginine and ornithine. In such species, this polypeptide may be treated as the beta subunit of an enzyme that may be named either arginine N-succinyltransferase (AST) or arginine and orthithine N-succinyltransferase (AOST).
ReferencesRN [1] RM PMID: 9393691 RT Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa. RA Itoh Y RL J Bacteriol. 1997 Dec;179(23):7280-90.
Genome PropertyGenProp0309: arginine catabolism to glutamate via arginine succinyltransferase (AST) (HMM)