HMM Summary Page: TIGR03237

FunctionDNA phosphorothioation-dependent restriction protein DptH
Gene SymboldptH
Trusted Cutoff620.65
Domain Trusted Cutoff620.65
Noise Cutoff423.35
Domain Noise Cutoff423.35
Isology Typeequivalog
HMM Length1256
Mainrole CategoryUnknown function
Subrole CategoryGeneral
AuthorHaft DH
Entry DateJan 4 2007 12:43PM
Last ModifiedFeb 10 2012 11:47AM
CommentA DNA sulfur modification (phosphorothioation) system, dnd (degradation during electrophoresis), is sparsely and sporadically distributed among the bacteria. This protein is one member of a three-gene restriction enzyme cassette that depends on DNA phosphorothioation.
ReferencesRN [1] RM PMID:20627870 RT A novel host-specific restriction system associated with DNA backbone S-modification in Salmonella. RA Xu T, Yao F, Zhou X, Deng Z, You D RL Nucleic Acids Res. 2010 Nov 1;38(20):7133-41. RN [2] RM PMID:22070167 RT ProPhylo: partial phylogenetic profiling to guide protein family construction and assignment of biological process. RA Basu MK, Selengut JD, Haft DH RL BMC Bioinformatics. 2011 Nov 9;12:434.
Genome PropertyGenProp0701: DNA sulfur modification system dnd (HMM)