HMM Summary Page: TIGR03235

Functioncysteine desulfurase DndA
Gene SymboldndA
Trusted Cutoff480.00
Domain Trusted Cutoff480.00
Noise Cutoff465.00
Domain Noise Cutoff465.00
Isology Typeequivalog
EC Number2.8.1.7
HMM Length353
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorHaft DH
Entry DateJan 4 2007 10:43AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes DndA, a protein related to IscS and part of a larger family of cysteine desulfurases. It is encoded, typically, divergently from a conserved, sparsely distributed operon for sulfur modification of DNA. This modification system is designated dnd, after the phenotype of DNA degradation during electrophoresis. The system is sporadically distributed in bacteria, much like some restriction enzyme operons. DndB is described as a putative ATPase.
ReferencesRN [1] RM PMID: 16102010 RT A novel DNA modification by sulphur. RA Zhou X, He X, Liang J, Li A, Xu T, Kieser T, Helmann JD, Deng Z RL Mol Microbiol. 2005 Sep;57(5):1428-38.
Genome PropertyGenProp0701: DNA sulfur modification system dnd (HMM)