HMM Summary Page: TIGR03230

Functionlipoprotein lipase
Trusted Cutoff822.75
Domain Trusted Cutoff822.75
Noise Cutoff658.90
Domain Noise Cutoff658.90
Isology Typeequivalog
EC Number3.1.1.34
HMM Length442
Gene Ontology TermGO:0004465: lipoprotein lipase activity molecular_function
AuthorHaft DH
Entry DateJan 2 2007 1:45PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are lipoprotein lipase (EC, a eukaryotic triacylglycerol lipase active in plasma and similar to pancreatic and hepatic triacylglycerol lipases (EC It is also called clearing factor. It cleaves chylomicron and VLDL triacylglycerols; it also has phospholipase A-1 activity.
ReferencesRN [1] RM PMID: 8308035 RT Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis. RA van Tilbeurgh H, Roussel A, Lalouel JM, Cambillau C RL J Biol Chem. 1994 Feb 11;269(6):4626-33.