| Accession | TIGR03224 |
| Name | benzo_boxA |
| Function | benzoyl-CoA oxygenase/reductase, BoxA protein |
| Gene Symbol | boxA |
| Trusted Cutoff | 459.20 |
| Domain Trusted Cutoff | 459.20 |
| Noise Cutoff | 260.80 |
| Domain Noise Cutoff | 260.80 |
| Isology Type | equivalog |
| EC Number | 1.14.12.21 |
| HMM Length | 411 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Other |
| Gene Ontology Term | GO:0010128: benzoate catabolic process via CoA ligation biological_process |
| | GO:0051213: dioxygenase activity molecular_function |
| Author | Haft DH |
| Entry Date | Dec 21 2006 2:36PM |
| Last Modified | Dec 12 2011 11:07PM |
| Comment | Members of this protein family are BoxA, the A component of the BoxAB benzoyl-CoA oxygenase/reductase. This oxygen-requiring enzyme acts in an aerobic pathway of benzoate catabolism via coenzyme A ligation. BoxA is a homodimeric iron-sulphur-flavoprotein and acts as an NADPH-dependent reductase for BoxB. |
| References | RN [1]
RM PMID: 15458418
RT New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii.
RA Zaar A, Gescher J, Eisenreich W, Bacher A, Fuchs G
RL Mol Microbiol. 2004 Oct;54(1):223-38.
RN [2]
RM PMID: 15916608
RT Aerobic benzoyl-CoA catabolic pathway in Azoarcus evansii: studies on the non-oxygenolytic ring cleavage enzyme.
RA Gescher J, Eisenreich W, Worth J, Bacher A, Fuchs G
RL Mol Microbiol. 2005 Jun;56(6):1586-600. |
| Genome Property | GenProp0709: benzoate catabolism BoxABC pathway (HMM) |
