HMM Summary Page: TIGR03222

Functionbenzoyl-CoA-dihydrodiol lyase
Gene SymbolboxC
Trusted Cutoff712.30
Domain Trusted Cutoff712.30
Noise Cutoff228.25
Domain Noise Cutoff228.25
Isology Typeequivalog
EC Number4.1.2.44
HMM Length548
Gene Ontology TermGO:0010128: benzoate catabolic process via CoA ligation biological_process
GO:0016787: hydrolase activity molecular_function
AuthorHaft DH
Entry DateDec 21 2006 1:38PM
Last ModifiedFeb 14 2011 3:27PM
CommentIn the presence of O2, the benzoyl-CoA oxygenase/reductase BoxBA BoxAB converts benzoyl-CoA to 2,3-dihydro-2,3-dihydroxybenzoyl-CoA. Members of this family, BoxC, homologous to enoyl-CoA hydratases/isomerases, hydrolyze this compound to 3,4-dehydroadipyl-CoA semialdehyde + HCOOH.
ReferencesRN [1] RM PMID: 15916608 RT Aerobic benzoyl-CoA catabolic pathway in Azoarcus evansii: studies on the non-oxygenolytic ring cleavage enzyme. RA Gescher J, Eisenreich W, Worth J, Bacher A, Fuchs G RL Mol Microbiol. 2005 Jun;56(6):1586-600.
Genome PropertyGenProp0709: benzoate catabolism BoxABC pathway (HMM)