HMM Summary Page: TIGR03218

Function4-oxalocrotonate decarboxylase
Gene SymboldmpH
Trusted Cutoff350.55
Domain Trusted Cutoff350.55
Noise Cutoff294.20
Domain Noise Cutoff294.20
Isology Typeequivalog
EC Number4.1.1.77
HMM Length263
Mainrole CategoryEnergy metabolism
Subrole CategoryOther
Gene Ontology TermGO:0047437: 4-oxalocrotonate decarboxylase activity molecular_function
AuthorHaft DH
Entry DateDec 19 2006 2:40PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are 4-oxalocrotonate decarboxylase. Note that this protein, as characterized (indirectly) in Pseudomonas sp. strain CF600, was inactive except when coexpressed with DmpE, 2-oxopent-4-enoate hydratase, a homologous protein from the same operon. Both of these enzymes are active in the degradation of catechol, a common intermediate in the degradation of aromatic compounds such as benzoate, toluene, phenol, dimethylphenol (dmp), salicylate, etc.
ReferencesRN [1] RM PMID: 1732207 RT Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600. RA Shingler V, Powlowski J, Marklund U RL J Bacteriol. 1992 Feb;174(3):711-24.
Genome PropertyGenProp0708: catechol meta-cleavage pathway (HMM)