HMM Summary Page: TIGR03212

Functionputative urate catabolism protein
Trusted Cutoff424.60
Domain Trusted Cutoff424.60
Noise Cutoff391.60
Domain Noise Cutoff391.60
Isology Typehypoth_equivalog_domain
HMM Length297
AuthorSelengut J
Entry DateDec 18 2006 11:15AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents a protein that is predominantly found just upstream of the UraD protein (OHCU decarboxylase) and in a number of instances as a N-terminal fusion with it. UraD itself catalyzes the last step in the catabolism of urate to allantoate [1]. The function of this protein is presently unknown. It shows homology with the PF01522 polysaccharide deacetylase domain family.
ReferencesRN [1] RM PMID: 16462750 RT Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes. RA Ramazzina I, Folli C, Secchi A, Berni R, Percudani R RL Nat Chem Biol. 2006 Mar;2(3):144-8. Epub 2006 Feb 5.
Genome PropertyGenProp0688: urate catabolism to allantoin (HMM)