HMM Summary Page: TIGR03211

Functioncatechol 2,3 dioxygenase
Trusted Cutoff320.20
Domain Trusted Cutoff320.20
Noise Cutoff237.95
Domain Noise Cutoff237.95
Isology Typeequivalog
EC Number1.13.11.2
HMM Length303
Mainrole CategoryEnergy metabolism
Subrole CategoryOther
Gene Ontology TermGO:0009712: catechol-containing compound metabolic process biological_process
GO:0018577: catechol 2,3-dioxygenase activity molecular_function
AuthorHaft DH
Entry DateDec 18 2006 9:59AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family all are enzymes active as catechol 2,3 dioxygenase (, although some members have highly significant activity on catechol derivatives such as 3-methylcatechol, 3-chlorocatechol, and 4-chlorocatechol (see Mars, et al.). This enzyme is also called metapyrocatechase, as it performs a meta-cleavage (an extradiol ring cleavage), in contrast to the ortho-cleavage (intradiol ring cleavage)performed by catechol 1,2-dioxygenase (EC, also called pyrocatechase.
ReferencesRN [1] RM PMID: 9973359 RT Conversion of 3-chlorocatechol by various catechol 2,3-dioxygenases and sequence analysis of the chlorocatechol dioxygenase region of Pseudomonas putida GJ31. RA Mars AE, Kingma J, Kaschabek SR, Reineke W, Janssen DB RL J Bacteriol. 1999 Feb;181(4):1309-18.
Genome PropertyGenProp0708: catechol meta-cleavage pathway (HMM)