| Accession | TIGR03201 |
| Name | dearomat_had |
| Function | 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase |
| Gene Symbol | had |
| Trusted Cutoff | 338.65 |
| Domain Trusted Cutoff | 338.65 |
| Noise Cutoff | 213.50 |
| Domain Noise Cutoff | 213.50 |
| Isology Type | equivalog |
| EC Number | 1.1.1.- |
| HMM Length | 349 |
| Gene Ontology Term | GO:0016491: oxidoreductase activity molecular_function |
| | GO:0019439: aromatic compound catabolic process biological_process |
| Author | Haft DH |
| Entry Date | Dec 12 2006 1:11PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase, an enzyme in the anaerobic metabolism of aromatic enzymes by way of benzoyl-CoA, as seen in Thauera aromatica, Geobacter metallireducens, and Azoarcus sp. The experimentally characterized form from T. aromatica uses only NAD+, not NADP+. Note that Rhodopseudomonas palustris uses a different pathway to perform a similar degradation of benzoyl-CoA to 3-hydroxpimelyl-CoA. |
| References | RN [1]
RM PMID: 10406950
RT 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase and 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, enzymes of the benzoyl-CoA pathway of anaerobic aromatic metabolism in the denitrifying bacterium Thauera aromatica.
RA Laempe D, Jahn M, Fuchs G
RL Eur J Biochem. 1999 Jul;263(2):420-9. |
| Genome Property | GenProp0706: cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway (HMM) |
