HMM Summary Page: TIGR03196

Functionxanthine dehydrogenase D subunit
Gene SymbolpucD
Trusted Cutoff783.65
Domain Trusted Cutoff783.65
Noise Cutoff665.15
Domain Noise Cutoff665.15
Isology Typeequivalog
EC Number1.17.1.4
HMM Length763
AuthorSelengut J
Entry DateDec 11 2006 3:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis gene has been characterized in B. subtilis [1] as the molybdopterin binding-subunit of xanthine dehydrogenase (pucD), acting in conjunction with pucC, the FAD-binding subunit and pucE, the FeS-binding subunit. The more common XDH complex (GenProp0640) includes the xdhB gene which is related to pucD. It appears that most of the relatives of pucD outside of this narrow clade are involved in other processes as they are found in unrelated genomic contexts, contain the more common XDH complex and/or do not appear to process purines to allantoin.
ReferencesRN [1] RM PMID: 11344136 RT Functional analysis of 14 genes that constitute the purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator. RA Schultz AC, Nygaard P, Saxild HH RL J Bacteriol. 2001 Jun;183(11):3293-302.
Genome PropertyGenProp0705: xanthine dehydrogenase, bacillus type (pucABCDE) (HMM)