| Accession | TIGR03188 |
| Name | histidine_hisI |
| Function | phosphoribosyl-ATP diphosphatase |
| Gene Symbol | hisE |
| Trusted Cutoff | 42.70 |
| Domain Trusted Cutoff | 42.70 |
| Noise Cutoff | 30.95 |
| Domain Noise Cutoff | 30.95 |
| Isology Type | equivalog_domain |
| EC Number | 3.6.1.31 |
| HMM Length | 84 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Histidine family |
| Gene Ontology Term | GO:0000105: histidine biosynthetic process biological_process |
| | GO:0004636: phosphoribosyl-ATP diphosphatase activity molecular_function |
| Author | Haft DH |
| Entry Date | Dec 6 2006 4:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme, phosphoribosyl-ATP pyrophosphohydrolase, catalyses the second step in the histidine biosynthesis pathway. It often occurs as a fusion protein. This model a somewhat narrower scope than Pfam model PF01503, as some paralogs that appear to be functionally distinct are excluded from this model. |
| References | DR PFAM; PF01503;
DR HAMAP; MF_01020; 209 of 210 |
| Genome Property | GenProp0109: histidine biosynthesis from ribose-5-phosphate (HMM) |
