HMM Summary Page: TIGR03182

Functionpyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
Gene SymbolpdhA
Trusted Cutoff393.85
Domain Trusted Cutoff393.85
Noise Cutoff371.65
Domain Noise Cutoff371.65
Isology Typeequivalog
EC Number1.2.4.1
HMM Length315
Mainrole CategoryEnergy metabolism
Subrole CategoryPyruvate dehydrogenase
Gene Ontology TermGO:0004739: pyruvate dehydrogenase (acetyl-transferring) activity molecular_function
GO:0006086: acetyl-CoA biosynthetic process from pyruvate biological_process
GO:0045250: cytosolic pyruvate dehydrogenase complex cellular_component
AuthorHaft DH
Entry DateDec 1 2006 2:54PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc.