Accession | TIGR03173 |
Name | pbuX |
Function | xanthine permease |
Gene Symbol | pbuX |
Trusted Cutoff | 414.15 |
Domain Trusted Cutoff | 414.15 |
Noise Cutoff | 371.25 |
Domain Noise Cutoff | 371.25 |
Isology Type | subfamily |
HMM Length | 407 |
Author | Selengut J |
Entry Date | Nov 29 2006 8:54AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696, [1]) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases. |
References | RN [1]
RM PMID: 9098051
RT Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism.
RA Christiansen LC, Schou S, Nygaard P, Saxild HH
RL J Bacteriol. 1997 Apr;179(8):2540-50. |
Genome Property | GenProp0696: xanthine utilization as a source of guanine-monophosphate (GMP) (HMM) |
| GenProp0698: xanthine catabolism to urate (HMM) |