HMM Summary Page: TIGR03162

Functionalpha-ribazole phosphatase
Gene SymbolcobC
Trusted Cutoff162.90
Domain Trusted Cutoff162.90
Noise Cutoff155.60
Domain Noise Cutoff155.60
Isology Typeequivalog
EC Number3.1.3.73
HMM Length176
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryHeme, porphyrin, and cobalamin
Gene Ontology TermGO:0009236: cobalamin biosynthetic process biological_process
GO:0019175: alpha-ribazole-5'-P phosphatase activity molecular_function
AuthorHaft DH
Entry DateNov 16 2006 1:59PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family include the known CobC protein of Salmonella and Eschichia coli species, and homologous proteins found in cobalamin biosynthesis regions in other bacteria. This protein is alpha-ribazole phosphatase (EC and, like many phosphatases, can be closely related in sequence to other phosphatases with different functions. Close homologs excluded from this model include proteins with duplications, so this model is built in -g mode to suppress hits to those proteins.
Genome PropertyGenProp0269: coenzyme B12 biosynthesis from cob(II)yrinate diamide (HMM)