HMM Summary Page: TIGR03148

Functioncytochrome c nitrite reductase, NrfD subunit
Gene SymbolnrfD
Trusted Cutoff347.60
Domain Trusted Cutoff347.60
Noise Cutoff300.15
Domain Noise Cutoff300.15
Isology Typeequivalog
EC Number1.7.2.2
HMM Length316
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
AuthorHaft DH
Entry DateNov 9 2006 9:27AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are NrfD, a highly hydrophobic protein encoded in the nrf operon, which encodes cytochrome c nitrite reductase. This multiple heme-containing enzyme can reduce nitrite to ammonia. Members belong to a broader PFAM protein family, PF03916, which also contains an NrfD-related subunit of polysulphide reductase.
ReferencesDR PFAM; PF03916; NrfD; Polysulphide reductase, NrfD RN [1] RM PMID: 8057835 RT A seven-gene operon essential for formate-dependent nitrite reduction to ammonia by enteric bacteria. RA Hussain H, Grove J, Griffiths L, Busby S, Cole J RL Mol Microbiol. 1994 Apr;12(1):153-63.
Genome PropertyGenProp0682: formate-dependent nitrite reductase, seven-gene type (HMM)