HMM Summary Page: TIGR03144

Functioncytochrome c-type biogenesis protein CcsB
Gene SymbolccsB
Trusted Cutoff187.60
Domain Trusted Cutoff187.60
Noise Cutoff138.75
Domain Noise Cutoff138.75
Isology Typeequivalog
HMM Length252
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
AuthorHaft DH
Entry DateNov 7 2006 3:38PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction.
ReferencesRN [1] RM PMID: 15937156 RT Mutations in cytochrome assembly and periplasmic redox pathways in Bordetella pertussis. RA Feissner RE, Beckett CS, Loughman JA, Kranz RG RL J Bacteriol. 2005 Jun;187(12):3941-9. DR HAMAP; MF_01391; 100 of 136
Genome PropertyGenProp0680: c-type cytochrome biogenesis, system II (HMM)