HMM Summary Page: TIGR03137

Gene SymbolahpC
Trusted Cutoff272.00
Domain Trusted Cutoff272.00
Noise Cutoff208.15
Domain Noise Cutoff208.15
Isology Typeequivalog
EC Number1.11.1.15
HMM Length187
Mainrole CategoryCellular processes
Subrole CategoryDetoxification
Gene Ontology TermGO:0006979: response to oxidative stress biological_process
GO:0051920: peroxiredoxin activity molecular_function
AuthorSelengut J
Entry DateNov 2 2006 11:39AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis [1] where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue.
ReferencesRN [1] RM PMID: 10482511 RT Role of the alkyl hydroperoxide reductase (ahpCF) gene in oxidative stress defense of the obligate Anaerobe bacteroides fragilis. RA Rocha ER, Smith CJ RL J Bacteriol. 1999 Sep;181(18):5701-10.
Genome PropertyGenProp0213: Resistance to Reactive Oxygen Species (ROS) (HMM)
GenProp0676: alkylhydroperoxide reductase AhpCF (peroxiredoxin) (HMM)