HMM Summary Page: TIGR03134

Functionbiotin-independent malonate decarboxylase, gamma subunit
Gene SymbolmdcE
Trusted Cutoff237.15
Domain Trusted Cutoff237.15
Noise Cutoff71.75
Domain Noise Cutoff71.75
Isology Typeequivalog
EC Number4.1.1.88
HMM Length258
AuthorHaft DH
Entry DateNov 1 2006 10:48AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the gamma subunit of malonate decarboxylase. Malonate decarboxylase may be a soluble enzyme, or linked to membrane subunits and active as a sodium pump. In the malonate decarboxylase complex, the beta subunit appears to act as a malonyl-CoA decarboxylase, while the gamma subunit appears either to mediate subunit interaction or to act as a co-decarboxylase with the beta subunit. The beta and gamma subunits exhibit some local sequence similarity.
ReferencesRF PFAM; PF06833; MdcE RN [1] RM PMID: 10561613 RT Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus. RA Koo JH, Kim YS RL Eur J Biochem. 1999 Dec;266(2):683-90.
Genome PropertyGenProp0674: malonate decarboxylase (HMM)