| Accession | TIGR03124 |
| Name | citrate_citX |
| Function | holo-ACP synthase CitX |
| Gene Symbol | citX |
| Trusted Cutoff | 105.25 |
| Domain Trusted Cutoff | 105.25 |
| Noise Cutoff | 57.15 |
| Domain Noise Cutoff | 57.15 |
| Isology Type | equivalog_domain |
| EC Number | 2.7.7.61 |
| HMM Length | 165 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Fermentation |
| Gene Ontology Term | GO:0050519: holo-citrate lyase synthase activity molecular_function |
| | GO:0051191: prosthetic group biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Oct 28 2006 10:40PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. |
| References | RN [1]
RM PMID: 11948157
RT Identification of a gene cluster in Klebsiella pneumoniae which includes citX, a gene required for biosynthesis of the citrate lyase prosthetic group.
RA Schneider K, Kastner CN, Meyer M, Wessel M, Dimroth P, Bott M
RL J Bacteriol. 2002 May;184(9):2439-46.
DR HAMAP; MF_00398; 18 of 19 |
| Genome Property | GenProp0672: citrate lyase system (HMM) |
