HMM Summary Page: TIGR03108

Functionexosortase A system-associated amidotransferase 1
Trusted Cutoff816.90
Domain Trusted Cutoff816.90
Noise Cutoff728.35
Domain Noise Cutoff728.35
Isology Typehypoth_equivalog
HMM Length628
AuthorHaft DH
Entry DateOct 16 2006 12:05PM
Last ModifiedJun 8 2011 1:45PM
CommentThe predicted protein-sorting transpeptidase that we call exosortase (see TIGR02602) has distinct subclasses that associated with different types of exopolysaccharide production loci. This model represents a distinct clade among a set of amidotransferases largely annotated (not necessarily accurately) as glutatime-hydrolyzing asparagine synthases. Members of this clade are essentially restricted to the characteristic exopolysaccharide (EPS) regions that contain the exosortase 1 genome (xrtA), in genomes that also have numbers of PEP-CTERM domain (TIGR02595) proteins.
ReferencesDR TIGRFAMS; TIGR02602 RN [1] RM PMID: 16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4:29.
Genome PropertyGenProp0652: exopolysaccharide biosynthesis, exosortase A-associated (HMM)