HMM Summary Page: TIGR03088

Functionsugar transferase, PEP-CTERM/EpsH1 system associated
Trusted Cutoff409.05
Domain Trusted Cutoff409.05
Noise Cutoff249.55
Domain Noise Cutoff249.55
Isology Typehypoth_equivalog
HMM Length374
AuthorSelengut J
Entry DateOct 5 2006 2:46PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family include a match to the PF00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria [1]. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.
ReferencesRN [1] RA Haft DH, Paulsen IT, Ward N, Selengut JD RT Exopolysaccharide-associated protein sorting in environmental organisms by the PEP-CTERM/EpsH system: application of a novel phylogenetic profiling heuristic.
Genome PropertyGenProp0652: exopolysaccharide biosynthesis, exosortase A-associated (HMM)