HMM Summary Page: TIGR03078

Functionmethane monooxygenase/ammonia monooxygenase, subunit C
Trusted Cutoff280.60
Domain Trusted Cutoff280.60
Noise Cutoff124.60
Domain Noise Cutoff124.60
Isology Typeequivalog
EC Number1.14.13.25
HMM Length231
AuthorHaft DH
Entry DateSep 22 2006 4:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentBoth ammonia oxidizers such as Nitrosomonas europaea and methanotrophs (obligate methane oxidizers) such as Methylococcus capsulatus each can grow only on their own characteristic substrate. However, both groups have the ability to oxidize both substrates, and so the relevant enzymes must be named here according to their ability to oxidze both. The protein family represented here reflects subunit C of both the particulate methane monooxygenase of methylotrophs and the ammonia monooxygenase of nitrifying bacteria.
ReferencesRN [1] RM PMID: 11233157 RT Differential inhibition in vivo of ammonia monooxygenase, soluble methane monooxygenase and membrane-associated methane monoxygenase by phenylacetylene. RA Lontoh S, DiSpirito AA, Krema CL, Whittaker MR, Hooper AB, Semrau JD RL Environ Microbiol. 2000 Oct;2(5):485-94.
Genome PropertyGenProp0666: membrane-associated monooxygenase (methane/ammonia) (HMM)