| Accession | TIGR03072 |
| Name | release_prfH |
| Function | putative peptide chain release factor H |
| Gene Symbol | prfH |
| Trusted Cutoff | 166.65 |
| Domain Trusted Cutoff | 166.65 |
| Noise Cutoff | 142.70 |
| Domain Noise Cutoff | 142.70 |
| Isology Type | equivalog |
| HMM Length | 200 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Translation factors |
| Gene Ontology Term | GO:0003747: translation release factor activity molecular_function |
| | GO:0006415: translational termination biological_process |
| Author | Haft DH |
| Entry Date | Sep 18 2006 10:45AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are bacterial proteins homologous to peptide chain release factors 1 (RF-1, product of the prfA gene), and 2 (RF-2, product of the prfB gene). The member from Escherichia coli K-12, designated prfH, appears to be a pseudogene. This class I release factor is always found as the downstream gene of a two-gene operon. |
| References | RN [1]
RM PMID: 16970810
RT Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons.
RA Baranov PV, Vestergaard B, Hamelryck T, Gesteland RF, Nyborg J, Atkins JF
RL Biol Direct. 2006 Sep 13;1(1):28. |
| Genome Property | GenProp0665: peptide chain release operon, RctB-like/PrfH (HMM) |
