HMM Summary Page: TIGR03070

Functiontranscriptional regulator, y4mF family
Trusted Cutoff71.65
Domain Trusted Cutoff71.65
Noise Cutoff61.30
Domain Noise Cutoff61.30
Isology Typesubfamily
HMM Length58
AuthorHaft DH
Entry DateSep 12 2006 4:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family PF01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems.