HMM Summary Page: TIGR03068

Functionsortase B signal domain, NPQTN class
Trusted Cutoff24.50
Domain Trusted Cutoff24.50
Noise Cutoff23.50
Domain Noise Cutoff23.50
Isology Typedomain
HMM Length33
AuthorHaft DH
Entry DateSep 8 2006 2:24PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents one of the boutique (rare) sortase signals, recognized by sortase B (SrtB) rather than by the housekeeping-type SrtA class sortase. This sequence, beginning NPQTN, shows little similarity to several other SrtB substrates.
ReferencesRN [1] RM PMID: 14762051 RT Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection. RA Weiss WJ, Lenoy E, Murphy T, Tardio L, Burgio P, Projan SJ, Schneewind O, Alksne L RL J Antimicrob Chemother. 2004 Mar;53(3):480-6. Epub 2004 Feb 4.
Genome PropertyGenProp0664: protein sorting system, sortase type, SrtB class (HMM)