HMM Summary Page: TIGR03028

Functionpolysaccharide export protein EpsE
Gene SymbolepsE
Trusted Cutoff262.65
Domain Trusted Cutoff262.65
Noise Cutoff166.90
Domain Noise Cutoff166.90
Isology Typeequivalog
HMM Length239
AuthorSelengut J
Entry DateJul 31 2006 2:25PM
Last ModifiedFeb 14 2011 3:27PM
CommentSequences in this family of proteins are members of a polysaccharide export protein family (PF02563) which includes the wza [1] protein from E.coli. This family of proteins are homologous to the EpsE protein of the methanolan biosynthesis operon of Methylobacillus species strain 12S [2]. The distribution of this protein appears to be restricted to a subset of exopolysaccharide operons containing a syntenic grouping of genes including a variant of the EpsH exosortase protein [2]. Exosortase has been proposed to be involved in the targetting and processing of proteins containing the PEP-CTERM domain to the exopolysaccharide layer [3].
ReferencesRN [1] RM 96326333 RT Organization of the Escherichia coli K-12 gene cluster RT responsible for production of the extracellular RT polysaccharide colanic acid. RA Stevenson G, Andrianopoulos K, Hobbs M, Reeves PR; RL J Bacteriol 1996;178:4885-4893. RN [2] RM 12624205 RA Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T RT Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S. RL Microbiology. 2003 Feb;149(Pt 2):431-44. RN [3] RA Haft DH, Paulsen IT, Ward N, Selengut JD RT Exopolysaccharide-associated protein sorting in environmental organisms by the PEP-CTERM/EpsH system: application of a novel phylogenetic profiling heuristic. RL BMC Biol., in press, 2006
Genome PropertyGenProp0655: exopolysaccharide biosynthesis, exosortase B-associated (HMM)