HMM Summary Page: TIGR03024

FunctionPEF-CTERM protein sorting domain
Trusted Cutoff23.00
Domain Trusted Cutoff23.00
Noise Cutoff22.00
Domain Noise Cutoff21.50
Isology Typedomain
HMM Length25
AuthorHaft DH
Entry DateJul 27 2006 3:42PM
Last ModifiedMar 18 2012 11:42AM
CommentThis domain, distantly related to the PEP-Cterm domain described in model TIGR02595, is found in Methanosarcina mazei in four different proteins, as well as in other archaea such as Methanococcoides burtonii. Several proteins with this domain have their genes only a short distance from archaeosortase C, a proposed integral membrane transpeptidase. This family should exclude members of the PEFG-CTERM domain family (TIGR04296), specific to the Thaumarchaeota.
ReferencesRN [1] RM PMID:22037399 RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification. RA Haft DH, Payne SH, Selengut JD RL J Bacteriol. 2012 Jan;194(1):36-48.
Genome PropertyGenProp0979: protein sorting system, PEF-CTERM/archaeosortase C (HMM)