HMM Summary Page: TIGR03014

Functionexopolysaccharide biosynthesis operon protein EpsL
Gene SymbolepsL
Trusted Cutoff309.60
Domain Trusted Cutoff309.60
Noise Cutoff210.75
Domain Noise Cutoff210.75
Isology Typehypoth_equivalog
HMM Length380
AuthorSelengut J
Entry DateJul 25 2006 9:32AM
Last ModifiedFeb 14 2011 3:27PM
CommentThe epsL gene is described as a component of the methanolan exopolysaccharide biosynthesis operon in Methylobacillus sp strain 12S [1], although no other information regarding its possible function is suggested. Homologs of this gene are found in several other exopolysaccharide operons in a small number of species. These operons contain a subset of the methanolan operon genes by homology and synteny, including the epsH gene which is proposed to act as an "exosortase" directing proteins with a C-terminal tag (PEP-CTERM) to the exopolysaccharide layer [2]. Each of the genomes in which these genes and epsL are found also encode genes with these C-terminal tags.
ReferencesRN [1] RM 12624205 RA Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T RT Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S. RL Microbiology. 2003 Feb;149(Pt 2):431-44. RN [2] RA Haft DH, Paulsen IT, Ward N, Selengut JD RT Exopolysaccharide-associated protein sorting in environmental organisms by the PEP-CTERM/EpsH system: application of a novel phylogenetic profiling heuristic. RL BMC Biol., in press, 2006
Genome PropertyGenProp0655: exopolysaccharide biosynthesis, exosortase B-associated (HMM)