Accession | TIGR02987 |
Name | met_A_Alw26 |
Function | type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family |
Trusted Cutoff | 353.50 |
Domain Trusted Cutoff | 353.50 |
Noise Cutoff | 116.10 |
Domain Noise Cutoff | 116.10 |
Isology Type | subfamily_domain |
EC Number | 2.1.1.72 |
HMM Length | 523 |
Mainrole Category | DNA metabolism |
Subrole Category | Restriction/modification |
Author | Haft DH |
Entry Date | Jun 28 2006 3:29PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this family are the m6-adenine DNA methyltransferase protein, or domain of a fusion protein that also carries m5 cytosine methyltransferase activity, of type II restriction systems of the Alw26I/Eco31I/Esp3I family. A methyltransferase of this family is alway accompanied by a type II restriction endonuclease from the Alw26I/Eco31I/Esp3I family (TIGR02986) and by an adenine-specific modification methyltransferase. Members of this family are unusual in that regions of similarity to homologs outside this family are circularly permuted. |
References | RN [1]
RM PMID: 12172806
RT Evolutionary relationship of Alw26I, Eco31I and Esp3I, restriction endonucleases that recognise overlapping sequences.
RA Bitinaite J, Mitkaite G, Dauksaite V, Jakubauskas A, Timinskas A, Vaisvila R, Lubys A, Janulaitis A
RL Mol Genet Genomics. 2002 Jul;267(5):664-72. Epub 2002 Jun 19. |
Genome Property | GenProp0650: type II restriction system, Alw26I/Eco31I/Esp3I family (HMM) |