HMM Summary Page: TIGR02968

Functionsuccinate dehydrogenase, hydrophobic membrane anchor protein
Gene SymbolsdhD
Trusted Cutoff41.80
Domain Trusted Cutoff41.80
Noise Cutoff39.30
Domain Noise Cutoff39.30
Isology Typeequivalog
HMM Length105
Mainrole CategoryEnergy metabolism
Subrole CategoryTCA cycle
Gene Ontology TermGO:0000104: succinate dehydrogenase activity molecular_function
GO:0006099: tricarboxylic acid cycle biological_process
GO:0045282: plasma membrane succinate dehydrogenase complex cellular_component
AuthorHaft DH
Entry DateJun 9 2006 1:23PM
Last ModifiedFeb 14 2011 3:27PM
CommentIn E. coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase, a TCA cycle enzyme, are SdhC and SdhD. This family is the SdhD, the hydrophobic membrane anchor protein. SdhC is apocytochrome b558, which also plays a role in anchoring the complex.
ReferencesRN [1] RM PMID: 8637872 RT Genes encoding the same three subunits of respiratory complex II are present in the mitochondrial DNA of two phylogenetically distant eukaryotes. RA Burger G, Lang BF, Reith M, Gray MW RL Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2328-32.
Genome PropertyGenProp0033: TCA cycle (HMM)