Accession | TIGR02967 |
Name | guan_deamin |
Function | guanine deaminase |
Gene Symbol | guaD |
Trusted Cutoff | 375.40 |
Domain Trusted Cutoff | 375.40 |
Noise Cutoff | 285.30 |
Domain Noise Cutoff | 285.30 |
Isology Type | equivalog |
EC Number | 3.5.4.3 |
HMM Length | 401 |
Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
Subrole Category | Other |
Gene Ontology Term | GO:0006147: guanine catabolic process biological_process |
| GO:0008892: guanine deaminase activity molecular_function |
Author | Haft DH |
Entry Date | Jun 9 2006 10:36AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model describes guanine deaminase, which hydrolyzes guanine to xanthine and ammonia. Xanthine can then be converted to urate by xanthine dehydrogenase, and urate subsequently degraded. In some bacteria, the guanine deaminase gene is found near the xdhABC genes for xanthine dehydrogenase. Non-homologous forms of guanine deaminase also exist, as well as distantly related forms outside the scope of this model. |
References | DR URL; http://www.brenda.uni-koeln.de/php/result_flat.php4?ecno=3.5.4.3
DR BRENDA; 3.5.4.3
RN [1]
RM PMID: 10913105
RT Identification, expression, and characterization of Escherichia coli guanine deaminase.
RA Maynes JT, Yuan RG, Snyder FF
RL J Bacteriol. 2000 Aug;182(16):4658-60. |
Genome Property | GenProp0698: xanthine catabolism to urate (HMM) |