HMM Summary Page: TIGR02956

FunctionTMAO reductase sytem sensor TorS
Gene SymboltorS
Trusted Cutoff676.50
Domain Trusted Cutoff676.50
Noise Cutoff446.00
Domain Noise Cutoff446.00
Isology Typeequivalog
EC Number2.7.13.3
HMM Length967
Mainrole CategorySignal transduction
Subrole CategoryTwo-component systems
Gene Ontology TermGO:0000156: two-component response regulator activity molecular_function
GO:0000160: two-component signal transduction system (phosphorelay) biological_process
GO:0004673: protein histidine kinase activity molecular_function
GO:0005524: ATP binding molecular_function
GO:0016020: membrane cellular_component
AuthorHaft DH
Entry DateJun 5 2006 10:09AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (PF02518), HAMP (PF00672), phosphoacceptor (PF00512), and phosphotransfer (PF01627) domains and a response regulator receiver domain (PF00072).
ReferencesRN [1] RM PMID: 16221580 RT Microbial dimethylsulfoxide and trimethylamine-N-oxide respiration. RA McCrindle SL, Kappler U, McEwan AG RL Adv Microb Physiol. 2005;50:147-98. RN [2] RM PMID: 8809780 RT An unorthodox sensor protein (TorS) mediates the induction of the tor structural genes in response to trimethylamine N-oxide in Escherichia coli. RA Jourlin C, Bengrine A, Chippaux M, Mejean V RL Mol Microbiol. 1996 Jun;20(6):1297-306.
Genome PropertyGenProp0638: trimethylamine N-oxide reductase system (HMM)