| Accession | TIGR02956 |
| Name | TMAO_torS |
| Function | TMAO reductase sytem sensor TorS |
| Gene Symbol | torS |
| Trusted Cutoff | 676.50 |
| Domain Trusted Cutoff | 676.50 |
| Noise Cutoff | 446.00 |
| Domain Noise Cutoff | 446.00 |
| Isology Type | equivalog |
| EC Number | 2.7.13.3 |
| HMM Length | 967 |
| Mainrole Category | Signal transduction |
| Subrole Category | Two-component systems |
| Gene Ontology Term | GO:0000156: two-component response regulator activity molecular_function |
| | GO:0000160: two-component signal transduction system (phosphorelay) biological_process |
| | GO:0004673: protein histidine kinase activity molecular_function |
| | GO:0005524: ATP binding molecular_function |
| | GO:0016020: membrane cellular_component |
| Author | Haft DH |
| Entry Date | Jun 5 2006 10:09AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (PF02518), HAMP (PF00672), phosphoacceptor (PF00512), and phosphotransfer (PF01627) domains and a response regulator receiver domain (PF00072). |
| References | RN [1]
RM PMID: 16221580
RT Microbial dimethylsulfoxide and trimethylamine-N-oxide respiration.
RA McCrindle SL, Kappler U, McEwan AG
RL Adv Microb Physiol. 2005;50:147-98.
RN [2]
RM PMID: 8809780
RT An unorthodox sensor protein (TorS) mediates the induction of the tor structural genes in response to trimethylamine N-oxide in Escherichia coli.
RA Jourlin C, Bengrine A, Chippaux M, Mejean V
RL Mol Microbiol. 1996 Jun;20(6):1297-306. |
| Genome Property | GenProp0638: trimethylamine N-oxide reductase system (HMM) |
