HMM Summary Page: TIGR02944

FunctionFeS assembly SUF system regulator
Trusted Cutoff110.65
Domain Trusted Cutoff110.65
Noise Cutoff104.20
Domain Noise Cutoff104.20
Isology Typeequivalog
HMM Length130
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0016226: iron-sulfur cluster assembly biological_process
GO:0016564: transcription repressor activity molecular_function
AuthorHaft DH
Entry DateMay 26 2006 12:17PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe SUF system is an oxygen-resistant iron-sulfur cluster assembly system found in both aerobes and facultative anaerobes. Its presence appears to be a marker of oxygen tolerance; strict anaerobes and microaerophiles tend to have different FeS cluster biosynthesis systems. Members of this protein family belong to the rrf2 family of transcriptional regulators and are found, typically, as the first gene of a SUF operon. It is found only in a subset of genomes that encode the SUF system, including the genus Xanthomonas. The conserved location suggests an autoregulatory role.
Genome PropertyGenProp0137: iron-sulfur cluster assembly SUF system (HMM)