HMM Summary Page: TIGR02920

Functionaccessory Sec system translocase SecY2
Gene SymbolsecY2
Trusted Cutoff249.60
Domain Trusted Cutoff249.60
Noise Cutoff222.55
Domain Noise Cutoff222.55
Isology Typeequivalog
HMM Length395
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0006886: intracellular protein transport biological_process
GO:0008565: protein transporter activity molecular_function
AuthorHaft DH
Entry DateApr 20 2006 3:37PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are restricted to the Firmicutes lineage (low-GC Gram-positive bacteria) and appear to be paralogous to, and much more divergent than, the preprotein translocase SecY. Members include the SecY2 protein of the accessory Sec system in Streptococcus gordonii, involved in export of the highly glycosylated platelet-binding protein GspB.
ReferencesRN [1] RM PMID:15901716 RT Two additional components of the accessory sec system mediating export of the Streptococcus gordonii platelet-binding protein GspB. RA Takamatsu D, Bensing BA, Sullam PM RL J Bacteriol. 2005 Jun;187(11):3878-83.
Genome PropertyGenProp0844: accessory Sec system for serine-rich glycoprotein transport (HMM)