HMM Summary Page: TIGR02917

Functionputative PEP-CTERM system TPR-repeat lipoprotein
Gene SymbolprsT
Trusted Cutoff312.20
Domain Trusted Cutoff312.20
Noise Cutoff217.45
Domain Noise Cutoff217.45
Isology Typeequivalog
HMM Length899
AuthorHaft DH
Entry DateApr 8 2006 8:13PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.
ReferencesRN [1] RM PMID: 16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4(1):29.
Genome PropertyGenProp0652: exopolysaccharide biosynthesis, exosortase A-associated (HMM)