HMM Summary Page: TIGR02916

Functionputative PEP-CTERM system histidine kinase
Gene SymbolprsK
Trusted Cutoff300.00
Domain Trusted Cutoff300.00
Noise Cutoff200.00
Domain Noise Cutoff200.00
Isology Typeequivalog
EC Number2.7.13.3
HMM Length679
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0000155: two-component sensor activity molecular_function
GO:0004673: protein histidine kinase activity molecular_function
AuthorHaft DH
Entry DateApr 7 2006 5:17PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family have a novel N-terminal domain, a single predicted membrane-spanning helix, and a predicted cystosolic histidine kinase domain. We designate this protein PrsK, and its companion DNA-binding response regulator protein (TIGR02915) PrsR. These predicted signal-transducing proteins appear to enable enhancer-dependent transcriptional activation. The prsK gene is often associated with exopolysaccharide biosynthesis genes.
ReferencesRN [1] RM PMID: 16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4(1):29.
Genome PropertyGenProp0652: exopolysaccharide biosynthesis, exosortase A-associated (HMM)